CBD Day!

February 1st is Leafly’s National CBD Day! To celebrate, GrowHealthy is re-releasing our CBD+: High CBD Frūtful™ Pineapple distillate, which is back by popular demand! In addition to the tinctures, patients can now purchase CBD+: High CBD Frūtful™ Pineapple cartridges and syringes.

 

We’ve all likely heard the term CBD, but when asked to explain it, the science can become a bit overwhelming. However, knowing what CBD is – especially the differences between hemp CBD and cannabis-derived CBD – can be incredibly helpful when patients are choosing the medicine that will be the best fit for them!

In our CBD blog post, we will explain what CBD is, the difference between hemp-derived and cannabis-derived CBD, the potential benefits of CBD, and the products GrowHealthy carries for our patients who are interested in trying a high CBD option.

What is CBD?

CBD is a therapeutic compound that is found in cannabis plants and hemp. This compound can be extracted from cannabis plants and hemp and used to make CBD oils, gummies, crème, salves, and other products. Essentially, CBD is a molecule of cannabis and hemp. THC is another molecule that is found in cannabis plants. These compounds, when inhaled, ingested, or applied, send messages to our brain that impact our physical and mental health.

An easy way to understand CBD, and how it is so effective, is to think about CBD as the ultimate brain communicator. CBD is interesting in that it mimics natural compounds that our bodies produce on their own. When we add CBD compounds to our body, it sends a message to our brains to produce more of the natural compounds.

Dr. Nick Jikomes does an excellent job explaining how CBD functions in the brain:

“[W]hen you ingest an edible or inhale some vapor, you’re allowing compounds originally produced by a plant to enter your body, travel through your bloodstream, and enter your brain. Once they arrive, these plant-derived compounds can influence brain activity by interacting with receptors on neurons. But they don’t interact with all neurons, just the ones that have the appropriate receptors.”

CBD enters your body and sends messages to your brain to encourage your body’s natural production of endocannabinoids. CBD compounds also interact with other receptor systems in our body and brain, including our opioid receptor system, dopamine receptor system, and serotonin receptor system.

All CBD is not the same, though. Both hemp and cannabis produce CBD, but they are both defined differently by law and can have different effects. Hemp, which was legalized in 2018, contains less than 0.3% of THC. Most CBD derived from hemp products are legal (but these can still differ by state). Hemp-derived CBD has also shown to not have any psychiatric effects, meaning that hemp-derived CBD cannot get you “high.” Most hemp-CBD products are widely available for purchase. However, hemp products, as Bailey Rahn warns, are not currently regulated. As such, unregulated products leave the possibilities of having “unreliable potencies, dubious claims, and questionable ingredients unchecked.”

Cannabis-derived CBD, on the other hand, is extremely regulated and is only available in states that have passed either recreational or medical marijuana laws.

Beyond being strictly regulated and tested, cannabis-derived CBD, according to Bailey Rahn, “produces a wider spectrum of therapeutic compounds (an in greater abundance) compared to hemp.”

Rahn continues to warn about the dangers of purchasing hemp-derived CBD: “Only CBD vapes sold in legal cannabis stores undergo mandated testing. CBD vapor products sold online or in smoke shops, gas stations, or other non-licensed shops are not currently held to the same strict regulations. It’s vitally important to be aware of the ingredients and additives in these vaping oils.”

At GrowHealthy, we only produce cannabis-derived CBD.

Next we explain how CBD interacts with our opioid, dopamine, and serotonin receptor symptoms, and we provide a list of CBD benefits.

Benefits of CBD

Because CBD molecules work with other receptors in the body, including opioid, dopamine, and serotonin, CBD can help reduce anxiety, relieve pain, decrease likelihood of addiction to pharmaceuticals, and reduce inflammation.

Anxiety

Research on CBD has shown that CBD can influence the activity in our serotonin system, which can lead to a decrease in anxiety. According to Emma Stone, CBD is becoming known for its therapeutic potential.  

In a 2019 case study, in which participants were given 25mg of CBD daily (in addition to other treatment), 79.2% of participants experienced an improvement in their reported anxiety within the first month. As Stone notes, though, 15% of these participants felt that their anxiety worsened. Patients should always speak with their doctors and test products in small amounts so they learn how different products affect them individually.

The way in which our bodies produce serotonin also impacts our general mood and anxiety. According to Dr. Nick Jikomes, CBD interacts with dopamine receptors, “which play a crucial role in regulating many aspects of behavior and cognition, including motivation and reward-seeking behavior.”

Pain

Katarina Kostovic reports that CBD can be great at dulling pain, such as prickling, tingling, and burning sensations. However, Kostovic cautions that CBD can be used to treat pain, but not all pain responds to CBD receptors. “Using CBD to treat pain can be effective,” she states, “only under the pretense that the type of pain is well understood and properly diagnosed.” CBD, she concludes, has shown to have the great impact on neuropathic and inflammatory pain.

Addiction

CBD is a promising and hopeful compound that can help thousands who are suffering from addiction. The opioid receptor system is one of our body’s systems with which CBD communicates. According to Bailey Rahn, CBD can help supplement and replace patients’ use of opioid painkillers, such as morphine, heroin, and fentanyl.  

Dr. Nick Jikomes also raises CBD’s possibility to dampen drug cravings and withdrawal symptoms, which are both associated with addiction. He concludes, however, that more research is needed.

Inflammation

According to Katarina Kostovic, CBD works great at calming inflammation. Cannabis-derived CBD also does not run the risk of causing stomach ulcers or heart attacks, unlike other anti-inflammatory products, such as ibuprofen.

Kostovic warns, however, that CBD has the potential to interact with medications, so always speak to your doctor before using CBD products. For more information on how cannabis can interact with other medications, refer to Jeremy Kossen’s helpful article here.

GrowHealthy High CBD Products and Modalities

Before we review our high CBD product offerings, it is important to know how different modalities (i.e., smoking, vaping, ingesting) impact CBD’s effects.

GrowHealthy primarily offers CBD distillate oil that can be ingested by tinctures or RSO application; CBD crèmes and salves that can be directly applied to the body, and CBD oil that can be vaporized using a cartridge.

Tinctures and RSO are longer-lasting and can be squeezed under the tongue or mixed in with food. Topicals provide localized relief from body pain and inflammation. Cartridges provide quick relief and can be great for those who suffer from anxiety and need relief fast.

If you aren’t sure how to use any of these modalities, please see our detailed instructions below. If you are already a pro, please feel free to scroll down to check out our High CBD product offerings, which include our Frūtful™ Pineapple distillate that is back by popular demand!

Tinctures

Shake the bottle well before use. Squeeze and release the rubber bulb with the tip of the dropper submerged in bottle. If consuming sublingually, administer under the tongue and let sit for at least 30-90 seconds before swallowing. It takes approximately 15-30 minutes to show its effect and lasts for up to 4-5 hours. If consuming orally, administer inside the mouth and swallow. Effects will be felt within approximately 1-2 hours can last 4-6 hours or longer. To apply topically, administer onto the skin, avoiding all open wounds. To monitor effects and manage your existing medical condition, begin with a dose of 0.5 mL (e.g., half of the dropper). Increase the dosage in 0.5 mL succession each day until you find the volume that is most effective.

RSO

Place the syringe in warm water for at least 30 seconds. Squeeze the metal plunger down to dispense an amount of approximately the size of a grain of rice (0.05 mg). If consuming orally, administer the medicine inside the mouth and swallow. To consume sublingually, administer medicine under the tongue and let sit for at least 30 seconds. For both oral and sublingual administration, it is recommended to eat something. Patients who consume RSO on an empty stomach may not experience the full effects. To apply topically, administer onto the skin, avoiding all open wounds, and cover with a bandage.

Topicals

Before application, wash affected area with soapy water. For best results, massage approximately 0.5 mL of product directly to the washed area. Repeat as frequently as needed for pain, swelling, and any other indications. It is advised to wait at least one hour after initial application to ensure no allergic reactions materialize before applying additional applications. Not for oral consumption. See topical ingredients below:

Crème – 50 mL (100 mg CBD | 100 mg THC) Ingredients: Lotion Base, Yuzu, Natures Oil Lemon Fragrance, and CO2. Extracted Dehydrated Crude.

Balm – 5 mL (100 mg CBD | 100 mg THC) Ingredients: Beeswax, Cocoa Butter, Shea Butter, Coconut Oil, Avocado Oil, Soy Lecithin, Vitamin E, Rosemary Essential Oil, Lemon Fragrance, and CO2. Extracted Dehydrated Crude.

Salve – 30 mL (250 mg CBD | 250 mg THC) Ingredients: Beeswax, Cocoa Butter, Shea Butter, Coconut Oil, Avocado Oil, Soy, Lecithin, Vitamin E, Rosemary Essential Oil, Lemon Fragrance, and CO2 Extracted Dehydrated Crude.

Cartridges

When using GrowHealthy cartridges, screw the cartridge onto a GrowHealthy battery. While drawing on the mouthpiece of the cartridge, a 3- second inhale will yield a dose of approximately 5 mg of cannabinoids. Inhalation usually quickens effect time and takes only 5-10 minutes before you start feeling the effects, with effects lasting for 2-4 hours.

If you are interested in trying cannabis-derived CBD products, here are a few that GrowHealthy offers!

 

Afghan Rubi – Available in RSO, cartridges, and syringes

Named for the geographic origins of one of its parents, Afghan Rubi crosses Pure Afghan and Rubicon. Combining these two strains creates a potent high-CBD formulation that’s great for nighttime medication, pain relief, or to reduce nausea. The flavor profile is pungent, earthy and citrus.

Patients have said:

“I use this for pain, sleep, anxiety, and to help my body use the THC more productively. I use it as a topical by putting lotion on first. If you can’t get past the taste of it you can get empty pill capsules and put in there. The taste is strong but that’s how your know it’s good! It makes sleep so much more productive for me. I dream happier and wake up feeling much more refreshed than without. I can’t live without my CBD. I used to think I’d never quit ThC but with CBD I consider it….”

“Incredible medicine! High CBD RSO saved me from a severe anxiety attack. I applied this behind my gums and let it absorb. Within minutes. my hyperventilating faded, racing thoughts gone and pulse returned to a much healthier place.”

CBD+: High CBD Frūtful™ Pineapple – Available in tinctures, cartridges, and syringes

Like a taste of the tropics, our pineapple-inspired Frūtful™ distillate is full of CBD and sweet, natural flavor. Designed to deliver full-body relaxation, this high CBD product is a tasty treat for instant relief – easing aches and inflammation while melting away pain.

Patients have said: 

“PLEASE Keep This Product!! I LOVE it so much! I have depression issues and so many of the regular medications I have tried make me feel like a zombie but this tincture makes me SMILE and brings back laughing and smiles that I have not had in a very long time and helps with pain issues.”

Coconut Yuzu Crème

Best for broad applications for all over body relaxation. Research shows 1:1 products are thought to reduce localized pain, inflammation, joint and muscle soreness, and muscle spasms.

Patients have said:

“I am a Fibromyalgia patient, this works GREAT for the muscle tightness, pain and neuropathy associated with fibro. This topical spreads easily and you only need a small amount to cover a larger area. Worked for me within minutes. Really impressed and glad I added this to my routine.”

“This stuff really works. I have neuropathy, and I use it on my legs before bed, and it really calms down the burning sensation. I get much better sleep as a result.”

 

We hope our patients enjoy CBD day!

REFERENCES:

Jikomes, N. (2016, October 10). CBD (cannabidiol): What does it do and how does it affect the brain & body. Leafly. https://www.leafly.com/news/cbd/what-does-cbd-do 
 
Kostovic, K. (2019, March 18). What types of pain can cannabidiol (CBD) treat? Leaflyhttps://www.leafly.com/news/health/cbd-types-of-pain 
 
Rahn, B. (2019, November 25). The complete guide to CBD (cannabidiol). Leafly
 
Shannon, S., et al. (2019, January 7). Cannabidiol in anxiety and sleep: A large case series. The Permanente Journal, 23, 18-41.
 
Stone, E. (2019, November 21). How to use CBD for anxiety. Leafly
 
–. (2019, November 22). What’s the difference between CBD derived from hemp and cannabis? Leafly. https://www.leafly.com/news/cbd/hemp-vs-cannabis-derived-cbd-whats-the-difference 

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